A New Path for Better Asthma Control! 

Struggling with asthma flare-ups?
You’re not alone. Join a research study exploring new treatment options designed to help you breathe easier and live better.

Living with asthma can be challenging, especially when symptoms like trouble breathing, coughing, wheezing, and chest tightness disrupt your daily life. Simple activities—like going for a walk, climbing stairs, or even sleeping through the night—can become difficult during flare-ups.  

While there’s no cure for asthma, finding the right treatment can make a big difference. Many people still struggle to keep their asthma symptoms fully under control.  

If you’re one of them, you’re not alone—there is ongoing research exploring new options to help better manage asthma and reduce flare-ups. Learn more about joining this new asthma study and get help finding a study site near you. 

Participants will meet with asthma research doctor while also continuing their regular asthma inhalers. AstraZeneca, the study sponsor will provide the study medicine at no cost. 


Study Overview

We’re looking for adults with asthma who experience frequent flare-ups to participate in an exciting new study! 

This research is testing an experimental medication designed to help better control asthma symptoms and experience less exacerbations (flare-ups).  
The study will evaluate how well this investigational treatment, given as a small injection under the skin every two weeks, can reduce asthma flare-ups and improve symptom management. If you or someone you know struggles with asthma control, this could be an opportunity to explore a potential new option. 

What is Asthma? 
Asthma is a common lung disease that causes inflammation and narrowing of the airways, leading to reduced airflow in and out of the lungs. This can result in symptoms such as coughing, wheezing and shortness of breath.  
Asthma is a chronic disease that affects millions of people and their families every day. Since there is not a cure for asthma, it is important to control symptoms of this disease. 

What are common asthma symptoms? 
Asthma symptoms may include trouble breathing, cough, wheezing and chest tightness. Currently, there is no cure for asthma and many people struggle to find a treatment plan that controls all of their symptoms.   


What is an exacerbation or flare-up? 

Asthma exacerbations (also known as flare-ups), happens when asthma symptoms suddenly worsen or become more frequent.  This can mean increased coughing, wheezing, shortness of breath, or chest tightness that lasts longer than usual. Flare-ups vary from person to person—some may experience mild symptoms, while others may have severe breathing difficulties that require medical attention. Understanding and managing flare-ups is key to keeping asthma under control. 

Recognizing the signs of an asthma flare-up  

  • Shortness of breath – feeling winded while doing normal activities  

  • Wheezing or coughing more than usual – especially at night or after exposure to your asthma triggers 

  • Chest tightness or pressure – like a heavy weight on your chest 

  • Changes in phlegm - more mucus or a different color than usual  

  • Frequent rescue inhaler use - needing a quick relief, more often 

  • Unusual tiredness – feeling drained even without much activity 

If these symptoms sound familiar, it might be time to explore new options to better manage your asthma and prevent flare-ups. If you are currently having difficulty breathing, contact your doctor right away or seek urgent medical care. 

Who can join the study?

We’re looking for individuals who struggle with asthma symptoms to take part in this research study.

You may qualify if you: 

  • Are between 18 and 75 years old 

  • Have been diagnosed with asthma 

  • Have had at least 1 flare-up in the past year 

  • Use a regular inhaler to manage your symptoms 

In order to enroll in the study, individuals must meet all of the study qualifications. 

What to expect: 

  • Meet with an asthma study doctor 

  • Participate in 12 in-person and 17 virtual check-ins (if you qualify) over 15 months 

  • Receive study medicine or an inactive substance (placebo) at no cost

  • Reimbursement may be available for your time and effort 

If asthma is still impacting your daily life, this study may be an opportunity to explore new treatment options! 


What to expect when joining an asthma study?

The pre-screening process 
If you are considering joining a study, the first step is to learn about the study and see if you meet the initial qualifications. To see if the study is a good fit for you, you'll answer health-related questions online.  
If you pass the online pre-screening questionnaire, you’ll be connected to a research site located nearest you. The research site will reach out to you directly. 

Pre-screening Questionnaire

Getting matched to a study site 
The study doctor and research team at that trial site will provide additional study information and guide you through the next steps.  
Study Sites conducting the study can be found here: ClinicalTrials.gov
You do not have to join the study if you do not want to, and you can change your mind at any time.  

The screening process and informed consent 
If you meet the pre-qualifications, you’ll be invited to the study site for an in-person visit to learn more about the study.  
At your appointment, the study doctor and research team will explain the study in-depth, including risks and benefits. They will also answer any questions you may have. 
If you are still interested in the study after speaking with the study doctor, you'll sign an informed consent document, confirming your willingness to join the study and undergo study assessments.   

Study activities will vary at each visit, but may include: 

  • Health-related questionnaires 

  • Brief physical exam 

  • Breathing Tests (Spirometry) 

  • Blood, urine and nose swab sample collection 

  • Electrocardiogram (ECG) 

Frequently Asked Questions

  • Clinical research is the process of testing and developing medicines to potentially prevent, treat, or manage diseases. Before any medicine becomes available, it must undergo clinical trials to ensure safety and effectiveness. 

  • This study is designed to see if an experimental medicine could potentially reduce asthma attack or flare-up symptoms and improve breathing.

  • You’ll help us learn about an experimental medicine to see if it could potentially be a new option in asthma treatment. 

  • No. All study-related care is provided at no cost, and you do not need healthcare to participate.  You will not have to pay for the experimental medicine, but your regular medications will not be paid for as part of the study.

  • Yes. Taking part in a study is always your choice. You can change your mind or stop taking part at any time, for any reason. 

  • Here are some useful links and language to provide patients to find more important information about asthma. 

    • Visit the American Lung Association's website for comprehensive information about asthma, including symptoms, causes, diagnosis, treatment, and management strategies 

      Asthma | American Lung Association

    • Asthma and Allergy Foundation of America (AAFA) - Explore the AAFA Foundation's patient resources for valuable information on asthma, including educational materials, support groups, and community resources 

      Asthma and Allergy Foundation of America | AAFA | Home

  • All participant data will be kept confidential and used only for research purposes. We follow strict privacy and security guidelines.